Cannabidiol is a component of the cannabis plant or useful hemp, which is assigned to the group of cannabinoids. The well-known THC (tetrahydrocannabinol), which leads to intentional or unintentional intoxication in drug users, also belongs to this group. CBD oil is not psychoactive. It does not put the user in another state of consciousness, no, it even counteracts such effects – but more about this later.
In commercial CBD oils and extracts, the cannabiodiol content almost always consists of one part CBD-A. This abbreviation stands for cannabidiol acid. CBD-A appears to be generally less extensive in its spectrum of action, but particularly effective in some areas. Decarboxylation can be achieved by heating the cannabidiol acid, which converts it into the neutral form.
CBD and THC are the cannabinoids naturally present in the largest concentration in the cannabis plant. Both substances are medically effective, but differ fundamentally:
Differences between CBD & THC
First, we want to separate cannabidiol from THC. The following points are particularly interesting:
- THC causes a state of intoxication, CBD works differently and does not change consciousness, is even able to prevent or reduce states of intoxication.
- THC is a non-legal or strictly prescription substance, while CBD oil is available for sale in Germany.
- THC increases appetite, cannabidiol on the other hand is more likely to reduce hunger.
- Cannabis varieties containing THC often have a negative effect on memory performance, CBD does not.
- THC can lead to anxiety and tachycardia, and cannabidiol is able to reduce or even prevent these effects.
Cannabidiol Trend in Science & Practice
Overshadowed by its big brother THC, the CBD led a shadowy existence for a long time – but that is over. Especially in the United States, which is becoming increasingly open to the benefits of cannabis, large sums of money are currently being invested in cannabidiol research. Driven by the great potential and medical benefit in a wide variety of conditions – arthritis, diabetes, cancer, anxiety disorders, migraine, depression, chronic pain, epilepsy and much more. – German scientists have also been trying to mobilise financial resources for several years.
Interest in CBD products is growing rapidly, not only in research but also among the world’s population. No wonder, since the first CBD experience reports on the Internet and in literature are extremely promising. CBD oil, CBD chewing gum, CBD spray or CBD liquid for the e-cigarette – the product range is growing and growing.
So far, most of the research results are still based on studies conducted in Vivo on human-like mammals (mice, rats, rabbits). Although 100% of these results cannot be transferred to humans, they give more than enough reason to see CBD as a substance with great therapeutic benefit.
So far we have only talked about the medical benefits, but even the supposedly healthy can benefit from cannabidiol. Whether acute in certain life situations or for general health maintenance – CBD offers versatile benefits for almost everyone.
- Are you sometimes uncomfortably excited and therefore unable to sleep?
- Are you particularly nervous before exams, lectures or job interviews?
- Do you ever have one over thirst?
These are just three examples that certainly apply to many of you. CBD oil has a relaxing, sleep-promoting, anxiety-relieving effect and can prevent nerve damage caused by alcohol. Sounds useful, doesn’t it? But we come to far more serious applications:
- Do you have chronic pain?
- Do you suffer from migraine attacks?
- Do you show symptoms of inflammatory diseases?
- Are you depressed or psychologically stressed?
- Are you seizures?
- Are you heading for a sugar disease?
- Are you on drug withdrawal?
- Are you dependent on THC for medication?
These are further selected conditions, for which there are already pioneering studies that point to successful therapy possibilities with cannabidiol. Do you find yourself in one of the points? Then make sure you read on.
CBD Side effects
The current study situation gives no reason to fear side effects from CBD. Bergamaschi et al. classified CDB oil in a 2011 meta-analysis as probably safe for humans and animals – even high doses of 1500mg per day are well tolerated by humans. Of course, the researchers also indicate here that further studies are needed to fully analyse CBD effects and side effects.
Caution seems to be required only for pregnancy – at least this is indicated by a study by Feinshtein et al. from 2013. Further information can be found here: ▷ CBD side effects.
User experiences and reports found on the Internet also do not indicate any undesirable effects to be expected. Please note the combination of certain drugs with CBD oil:
Cannabidiol inhibits the cytochrome P450 enzymes CYP2C19 and CYP2D6 in the liver, which means that certain drugs that are broken down by these enzymes remain in the bloodstream for longer. Examples of such drugs are the epilepsy drug diazepam or the proton pump inhibitor omeprazole.
Although much pioneering work still needs to be done, current studies already show how broad the potential spectrum of action of cannabidiol could be. It is hardly possible to mention all the positive effects, but we would like to give you a brief overview of the mode of action with the following list:
- Analgesic: CBD is able to inhibit pain (e.g. migraine or menstrual complaints)
- Anti-inflammatory: Cannabidiol can reduce acute and chronic inflammation in the body
- Anorexic: CBD oil reduces appetite and is therefore a potential helper in cases of obesity.
- Antiemetic: It acts against nausea and nausea and is therefore e.g. a help with travel sicknesses.
- Anti-kinetic: In many cases a calming effect on the intestinal tract could be shown
- Anxiolytic: Cannabidiol reduces excessive anxiety and related symptoms
- Neuroleptic: It has effectively contained loss of reality, hallucinations and delusions.
- Antiepileptic: Some studies suggest effective use against epilepsy
- Antispasmodic: cramps and tension can be relieved by CBD
- Antiinsomnia: the active ingredient seems to be suitable as a sleep aid
- Immunosuppressive: animal studies show success in allergies and hypersensitivity
- Antidiabetic: Scientists suggest that CBD could prevent diabetes and reduce its consequences
- Neuroprotective: Cannabidiol could be effective against dementia or Alzheimer’s disease
- Antipsoriatic: regulation of skin regeneration and treatment of psoriasis and other skin diseases
- Anti-ischemic: CBD oil has been shown in some studies to reduce blood circulation in tissues
- Antibacterial: Cannabidiol is also effective against highly antibiotic-resistant bacteria (e.g. MSRA)
- Antifungal: CBD(-A) is able to fight fungal infections
- Antiproliferative: It has been observed that it counteracts the growth of cancer cells
How does CBD still work?
It also increases the stability of bones, is suitable for combating addiction and helps with many chronic diseases (e.g. rheumatism, diabetes, autism, Crohn’s disease, heart/liver/renal diseases, schizophrenia). These are all possible areas of application that current basic research holds out the prospect of – and new CBD experiences are published daily on the Internet.
Cannabidiol relaxes and soothes
Overall, I would describe the effect of CBD as relaxing – both psychologically and physically – and symptom-relieving. CBD does not heal in the first place, but it provides relief for many ailments related to nerves and psyche.
Whether it is the recurring headaches, sleep disorders, chronic inflammation or nerve disorders. CBD helps to deal with these symptoms, reduce them or even eliminate them. This effect should not be underestimated, as it promotes general well-being and helps the body to help itself. These effects can also contribute to the support of other therapies (e.g. chemo).
All this refers to the studies carried out so far, which are still in their infancy, but definitely suggest that cannabidiol could bring a lot to many of us.
How long does it last? How quickly does it work? These questions can hardly be answered across the board – so: in this case, trying really is more than studying.
This area is actually divided into two questions. So let’s first look at the question “Where to buy” and then clarify what to look for when choosing a product.
In 2015 and 2016, the U.S. Food and Drug Administration, the U.S. Food and Drug Administration, published so-called “Warning Letter and Test Results” (to be found here). It lists many of the common CBD preparations that the authority has tested for their ingredients. It turned out that by no means every product contains what it should contain according to the label.
Some of these products are now also available in Germany. However, an examining look on our part did not find any dubious preparations that also made it onto our market. However, considering that there are many other manufacturers and cannabidiol products today, a risk cannot be ruled out. Therefore:
Buy your CBD oil or other cannabidiol products only from trusted and reputable retailers.
Which cannabidiol product should I buy?
Cannabidiol is available in a variety of dosage forms, including…
- … CBD oil or drops
- … chewing gums
- … Spray
- … Liquid for the e-cigarette
- … Capsules
- … paste
Cannabidiol oil is the most common and usually the cheapest. It usually contains natural hemp oil, together with 2 – 10% CBD and less than 0.2% THC. The essential oils contained in it also form part of the active substance construct.
When buying, you should clarify in advance which CBD dosage is suitable for you. In some people, even in small doses, it has the desired effect. On the other hand, there are more serious diseases that require a correspondingly high daily intake. Since there is still a need for research here as well, we can certainly not give you an optimal recommendation.
So which CBD oil should it be? Take a look at our buying advice: ▷ Buy CBD oil
There is no general recommendation for intake and dosage. This is not only due to the need for further studies, but also to the fact that both should be adapted individually. Some examples:
- A woman with migraine reports that already 3-5 drops help her to an acute relief of her pain.
- Studies have shown that a good 30mg could be effective in helping with anxiety.
- Sleep problems seem to have the desired effect from a few drops up to 30mg.
- Doses of 100, 300 or even 1000 mg per day are also used for diseases such as diabetes or mental disorders.
It has been shown that people react very differently to cannabidiol and that the rule of thumb “just try it out and slowly approach the dose” works best. Especially with problems such as migraine, menstrual problems or sleep disorders, it has proven to be a good idea to proceed in this way. For more serious illnesses, the advice of a physician should be sought.
How often should I/may I take cannabidiol oil (CBD oil)?
CBD oil has no addictive potential – i.e. users develop neither physical nor mental dependence. Some study results regarding the anxiety-killing effect suggest that a cyclical intake is advantageous in contrast to continuous intake. We dare not judge at this point whether this is generally true or whether it is meaningful at all.
As a rule, you can take cannabidiol whenever acute problems occur – for example, when you feel that a migraine attack is imminent. However, there is no reason why chronic conditions such as allergies, inflammatory diseases or psychological symptoms should not be taken continuously.
© Copyright 2018
We wish you much success and pleasure with the information on CBD360, remember: it is our experience on our website and not recommendations – we can & must not give medical advice.